1 00:00:00,150 --> 00:00:02,500 [Music] 2 00:00:02,500 --> 00:00:02,510 [Music] 3 00:00:02,510 --> 00:00:06,230 [Music] if you take in less energy then you take 4 00:00:06,230 --> 00:00:06,240 if you take in less energy then you take 5 00:00:06,240 --> 00:00:08,810 if you take in less energy then you take out then you will lose weight and and 6 00:00:08,810 --> 00:00:08,820 out then you will lose weight and and 7 00:00:08,820 --> 00:00:11,749 out then you will lose weight and and that idea of course it has some truth to 8 00:00:11,749 --> 00:00:11,759 that idea of course it has some truth to 9 00:00:11,759 --> 00:00:14,660 that idea of course it has some truth to it but then it also oversimplifies the 10 00:00:14,660 --> 00:00:14,670 it but then it also oversimplifies the 11 00:00:14,670 --> 00:00:17,359 it but then it also oversimplifies the situation and we know that this is also 12 00:00:17,359 --> 00:00:17,369 situation and we know that this is also 13 00:00:17,369 --> 00:00:20,269 situation and we know that this is also definitely not the full answer to it so 14 00:00:20,269 --> 00:00:20,279 definitely not the full answer to it so 15 00:00:20,279 --> 00:00:22,700 definitely not the full answer to it so my name is Aaron Segal I'm a researcher 16 00:00:22,700 --> 00:00:22,710 my name is Aaron Segal I'm a researcher 17 00:00:22,710 --> 00:00:24,620 my name is Aaron Segal I'm a researcher at the Weizmann Institute of Science you 18 00:00:24,620 --> 00:00:24,630 at the Weizmann Institute of Science you 19 00:00:24,630 --> 00:00:26,630 at the Weizmann Institute of Science you can have a diet where people even eat 20 00:00:26,630 --> 00:00:26,640 can have a diet where people even eat 21 00:00:26,640 --> 00:00:30,140 can have a diet where people even eat more calories than some other person yet 22 00:00:30,140 --> 00:00:30,150 more calories than some other person yet 23 00:00:30,150 --> 00:00:32,450 more calories than some other person yet they still lose more weight and even the 24 00:00:32,450 --> 00:00:32,460 they still lose more weight and even the 25 00:00:32,460 --> 00:00:37,760 they still lose more weight and even the same person on diet a can eat say 2,000 26 00:00:37,760 --> 00:00:37,770 same person on diet a can eat say 2,000 27 00:00:37,770 --> 00:00:40,280 same person on diet a can eat say 2,000 calories and gain weight but then on 28 00:00:40,280 --> 00:00:40,290 calories and gain weight but then on 29 00:00:40,290 --> 00:00:43,520 calories and gain weight but then on another diet that person would eat 2500 30 00:00:43,520 --> 00:00:43,530 another diet that person would eat 2500 31 00:00:43,530 --> 00:00:45,290 another diet that person would eat 2500 calories but they would be losing weight 32 00:00:45,290 --> 00:00:45,300 calories but they would be losing weight 33 00:00:45,300 --> 00:00:48,979 calories but they would be losing weight and and the reason is because the foods 34 00:00:48,979 --> 00:00:48,989 and and the reason is because the foods 35 00:00:48,989 --> 00:00:50,810 and and the reason is because the foods in these different diets may be very 36 00:00:50,810 --> 00:00:50,820 in these different diets may be very 37 00:00:50,820 --> 00:00:52,880 in these different diets may be very different and may be processed very 38 00:00:52,880 --> 00:00:52,890 different and may be processed very 39 00:00:52,890 --> 00:00:55,490 different and may be processed very differently by the individual and it has 40 00:00:55,490 --> 00:00:55,500 differently by the individual and it has 41 00:00:55,500 --> 00:00:58,130 differently by the individual and it has to do with the amount of energy that 42 00:00:58,130 --> 00:00:58,140 to do with the amount of energy that 43 00:00:58,140 --> 00:01:00,229 to do with the amount of energy that that individual may be able to extract 44 00:01:00,229 --> 00:01:00,239 that individual may be able to extract 45 00:01:00,239 --> 00:01:02,029 that individual may be able to extract from one diet compared to the other and 46 00:01:02,029 --> 00:01:02,039 from one diet compared to the other and 47 00:01:02,039 --> 00:01:05,899 from one diet compared to the other and we really think that a key aspect for 48 00:01:05,899 --> 00:01:05,909 we really think that a key aspect for 49 00:01:05,909 --> 00:01:09,080 we really think that a key aspect for measuring that has to do with your blood 50 00:01:09,080 --> 00:01:09,090 measuring that has to do with your blood 51 00:01:09,090 --> 00:01:11,420 measuring that has to do with your blood glucose level response to those foods 52 00:01:11,420 --> 00:01:11,430 glucose level response to those foods 53 00:01:11,430 --> 00:01:13,910 glucose level response to those foods because that really dictates then the 54 00:01:13,910 --> 00:01:13,920 because that really dictates then the 55 00:01:13,920 --> 00:01:15,679 because that really dictates then the amount of insulin that your body 56 00:01:15,679 --> 00:01:15,689 amount of insulin that your body 57 00:01:15,689 --> 00:01:17,780 amount of insulin that your body secretes and that is directly affecting 58 00:01:17,780 --> 00:01:17,790 secretes and that is directly affecting 59 00:01:17,790 --> 00:01:21,920 secretes and that is directly affecting the amount of fat storage that will be 60 00:01:21,920 --> 00:01:21,930 the amount of fat storage that will be 61 00:01:21,930 --> 00:01:24,140 the amount of fat storage that will be caused by consumption of these foods one 62 00:01:24,140 --> 00:01:24,150 caused by consumption of these foods one 63 00:01:24,150 --> 00:01:27,020 caused by consumption of these foods one of the reasons why you really see this 64 00:01:27,020 --> 00:01:27,030 of the reasons why you really see this 65 00:01:27,030 --> 00:01:29,569 of the reasons why you really see this phenomena that on the same food some 66 00:01:29,569 --> 00:01:29,579 phenomena that on the same food some 67 00:01:29,579 --> 00:01:31,249 phenomena that on the same food some person would gain weight and another 68 00:01:31,249 --> 00:01:31,259 person would gain weight and another 69 00:01:31,259 --> 00:01:33,560 person would gain weight and another person would lose weight a lot of that 70 00:01:33,560 --> 00:01:33,570 person would lose weight a lot of that 71 00:01:33,570 --> 00:01:36,350 person would lose weight a lot of that we believe has to do with differences 72 00:01:36,350 --> 00:01:36,360 we believe has to do with differences 73 00:01:36,360 --> 00:01:38,359 we believe has to do with differences that we have in our gut bacteria because 74 00:01:38,359 --> 00:01:38,369 that we have in our gut bacteria because 75 00:01:38,369 --> 00:01:41,179 that we have in our gut bacteria because the gut bacteria would be processing and 76 00:01:41,179 --> 00:01:41,189 the gut bacteria would be processing and 77 00:01:41,189 --> 00:01:44,030 the gut bacteria would be processing and being involved in metabolizing the foods 78 00:01:44,030 --> 00:01:44,040 being involved in metabolizing the foods 79 00:01:44,040 --> 00:01:46,999 being involved in metabolizing the foods very differently in each person so each 80 00:01:46,999 --> 00:01:47,009 very differently in each person so each 81 00:01:47,009 --> 00:01:49,580 very differently in each person so each of us actually has a tremendous amount 82 00:01:49,580 --> 00:01:49,590 of us actually has a tremendous amount 83 00:01:49,590 --> 00:01:51,889 of us actually has a tremendous amount of different bacteria living within 84 00:01:51,889 --> 00:01:51,899 of different bacteria living within 85 00:01:51,899 --> 00:01:54,410 of different bacteria living within within our body some bacteria will 86 00:01:54,410 --> 00:01:54,420 within our body some bacteria will 87 00:01:54,420 --> 00:01:56,810 within our body some bacteria will thrive on some food and other bacteria 88 00:01:56,810 --> 00:01:56,820 thrive on some food and other bacteria 89 00:01:56,820 --> 00:01:58,760 thrive on some food and other bacteria will thrive on other foods they're 90 00:01:58,760 --> 00:01:58,770 will thrive on other foods they're 91 00:01:58,770 --> 00:02:01,429 will thrive on other foods they're really heavily intertwined with our 92 00:02:01,429 --> 00:02:01,439 really heavily intertwined with our 93 00:02:01,439 --> 00:02:04,459 really heavily intertwined with our metabolism and have an enormous impact 94 00:02:04,459 --> 00:02:04,469 metabolism and have an enormous impact 95 00:02:04,469 --> 00:02:07,370 metabolism and have an enormous impact on our processing of food and on our 96 00:02:07,370 --> 00:02:07,380 on our processing of food and on our 97 00:02:07,380 --> 00:02:09,169 on our processing of food and on our health and disease and they've been 98 00:02:09,169 --> 00:02:09,179 health and disease and they've been 99 00:02:09,179 --> 00:02:11,150 health and disease and they've been linked to many different disease to 100 00:02:11,150 --> 00:02:11,160 linked to many different disease to 101 00:02:11,160 --> 00:02:12,420 linked to many different disease to obesity 102 00:02:12,420 --> 00:02:12,430 obesity 103 00:02:12,430 --> 00:02:14,910 obesity diabetes heart disease and even to 104 00:02:14,910 --> 00:02:14,920 diabetes heart disease and even to 105 00:02:14,920 --> 00:02:17,880 diabetes heart disease and even to cancer and neurological disease we are 106 00:02:17,880 --> 00:02:17,890 cancer and neurological disease we are 107 00:02:17,890 --> 00:02:20,309 cancer and neurological disease we are still as a scientific community trying 108 00:02:20,309 --> 00:02:20,319 still as a scientific community trying 109 00:02:20,319 --> 00:02:22,589 still as a scientific community trying to understand what is a good and what is 110 00:02:22,589 --> 00:02:22,599 to understand what is a good and what is 111 00:02:22,599 --> 00:02:25,619 to understand what is a good and what is a bad bacterial composition and how we 112 00:02:25,619 --> 00:02:25,629 a bad bacterial composition and how we 113 00:02:25,629 --> 00:02:28,229 a bad bacterial composition and how we can also change that with diet and this 114 00:02:28,229 --> 00:02:28,239 can also change that with diet and this 115 00:02:28,239 --> 00:02:30,509 can also change that with diet and this is very much an active field of research 116 00:02:30,509 --> 00:02:30,519 is very much an active field of research 117 00:02:30,519 --> 00:02:33,360 is very much an active field of research that we are trying to understand but in 118 00:02:33,360 --> 00:02:33,370 that we are trying to understand but in 119 00:02:33,370 --> 00:02:36,020 that we are trying to understand but in the meantime we've been able to profile 120 00:02:36,020 --> 00:02:36,030 the meantime we've been able to profile 121 00:02:36,030 --> 00:02:38,699 the meantime we've been able to profile individuals gut bacterial composition 122 00:02:38,699 --> 00:02:38,709 individuals gut bacterial composition 123 00:02:38,709 --> 00:02:41,729 individuals gut bacterial composition and based on their composition identify 124 00:02:41,729 --> 00:02:41,739 and based on their composition identify 125 00:02:41,739 --> 00:02:45,000 and based on their composition identify foods that would be fitting and matching 126 00:02:45,000 --> 00:02:45,010 foods that would be fitting and matching 127 00:02:45,010 --> 00:02:47,550 foods that would be fitting and matching their own bacterial composition so while 128 00:02:47,550 --> 00:02:47,560 their own bacterial composition so while 129 00:02:47,560 --> 00:02:50,339 their own bacterial composition so while we still do not understand the full way 130 00:02:50,339 --> 00:02:50,349 we still do not understand the full way 131 00:02:50,349 --> 00:02:52,470 we still do not understand the full way by which we can affect the gut bacteria 132 00:02:52,470 --> 00:02:52,480 by which we can affect the gut bacteria 133 00:02:52,480 --> 00:02:54,059 by which we can affect the gut bacteria for the better 134 00:02:54,059 --> 00:02:54,069 for the better 135 00:02:54,069 --> 00:02:57,270 for the better we can utilize and harness the 136 00:02:57,270 --> 00:02:57,280 we can utilize and harness the 137 00:02:57,280 --> 00:02:59,039 we can utilize and harness the information in the gut bacterial 138 00:02:59,039 --> 00:02:59,049 information in the gut bacterial 139 00:02:59,049 --> 00:03:01,559 information in the gut bacterial composition in order to tailor the diet 140 00:03:01,559 --> 00:03:01,569 composition in order to tailor the diet 141 00:03:01,569 --> 00:03:04,679 composition in order to tailor the diet of an individual to find foods that 142 00:03:04,679 --> 00:03:04,689 of an individual to find foods that 143 00:03:04,689 --> 00:03:22,740 of an individual to find foods that would be optimal for that person 144 00:03:22,740 --> 00:03:22,750 145 00:03:22,750 --> 00:03:24,810 you